Allergic Aspects of IgG4-Related Disease: Implications for Pathogenesis and Therapy
IgG4-related disease (IgG4-RD) is a rare systemic fibroinflammatory disease frequently associated with allergy.The pathogenesis of IgG4-RD is poorly understood, and effective therapies are limited.However, IgG4-RD appears to involve some of the same pathogenic mechanisms observed in allergic disease, such as T helper 2 (Th2) and regulatory T cell M